Summary: Or use at your own risk. It took me a month to isolate problems after installing Crucial memory in the computer. Bought what EPSON recommended, the Belkin 2.0 card. It froze the EPSON Smart Panel. The essiscsi.dll dissapeared from the registry. The ecbteg.dll and ebpport.dll could not be found. The new SmartPanel and Twain driver from the epson.com does not work in Windows ME.
Summary: I have been extremly disappointed by this scanner, likely the problem is the software, tried to use their help, not toll free, and found it less than helpful, as if they didn't care. Tried to find the software patch, and the support web site was not helpful and when I make another phone call, got no help that solved the problems. Was advised to buy another operating system, don't think that is the answer. Would not recommentd this scanner.
Summary: What a nightmare! DO NOT BUY THIS SCANNER, especially if you are buying it as a replacement for a current scanner. The software being shipped with this product conflicts with previously installed scanner software (even if you've uninstalled the old scanners software). Technical support, which is NOT toll-free is awful. What's worse? When you go to the Epson website to download the current patch files for the bad software that was shipped, it doesn't work!