Summary: While it isn't top class in terms of what you can do (several JP products do a better job and depending on your goal, some EN products may be better), it has some good things going. It is one of the better EN products for making rpg games. As it is fairly simple to use up to a certain extent, it can be a great tool for people who are fairly casual and just have passing interests.
Summary: This is the perfect tool to make the RPG of your choice! ...okay, like with all things, work must be put into making games, even with RPG Maker. However, if you've heard the saying "you reap what you sow", then you'll know that all the effort you put into whatever game you make will be immensely worth it... especially if you mess around with the program enough to need to bug-hunt mistakes you are likely to make.
Summary: This product will take you as far as you want to go, or as casual as you might need. I bought it recently and I have been learning so much and creating my dream psx / snes era game that has been sitting in my head for years. I never thought that making a game would be this easy, not only that but the ceiling for skill in this puppy is suprisingly high. I am just now breaking into the flexible ruby scripting language and going off from there.
Summary: Just to avoid any confusion... RPG Maker VX Ace is an awesome program which allows anyone with a story idea or game concept to build a game pretty close to what they have in their head. You can always go out of your way to customize graphics, music, game systems, or whatever else you desire, but the system ships with good defaults that let you focus soley on the story.
Summary: The engine is powerful, but there is a learning curve for 'eventing', scripting, and most of all debugging. Should you get past the basics this software can provide a rich and rewarding experience of making your own games with custom graphics, sounds, music, and more. You do not need any sort of talent for the aforementioned as they are available non commercially and commercially for use at your discretion.
Summary: Even though this technically isn't a "game", it's a great program that delivers to both beginners and professionals. A large portion of what makes RPG Maker VX Ace great is its dedicated and super helpful community. In my time using VX Ace, I have never come across an issue that someone couldn't help me with.