Pros: Has one full strength (x16) PCI-E slot for a killer vid card, plus has two reg 32bit PCI slots for my 7.1 sound card and a firewire card. I can still use my IDE DVD/CD...
Cons: None unless you want to run SLI or CrossfireX with 2 video cards, or if you want to move up to USB 3.0 or SATA 6 GB.