Summary: This and the AMD/ATI FirePro W5000 seem the best value in CAD gpu's right now. More performance than ever before and the fair price point of $400. Until your software vendor can prove, substantiate, and quantify improved performance, these are all the card you'll need for your CAD workstation. I bought the FirePro W5000 last year when there was a ~$200 rebate.
Summary: I'm not a gamer but am using this card on a new Asus Maximus VI Hero board to do some work using Photoshop and After Effects. I'm using dual monitors, main one is a ViewSonic VX2452MH 24-Inch and the smaller one which I had previously is a ViewSonic VA2037A-LED 20-Inch. As a novice, I wanted to get something good but not spend much more than about $300 for a card.
Summary: I use Maya, Mudbox, ZBrush, RealFlow, Photoshop, etc. And this card performs well. If you know you need one and you're using programs that really use a workstation card's power/architecture correctly, you won't be disappointed. Can even handle light gaming. I've always been more of a Quadro person, rather than FirePro, when it comes to workstation cards. I feel like Nvidia's drivers are better, but that's just me.
Excerpt: I cracked open my workstation, installed the Quadro K20000, and had it running in about 10 minutes. I wanted to test the performance of this graphics card over my previous one, so I opened a detailed 3D scene I've been working on and made sure all the quality settings were maxed out. Where before the scene was laggy and hard to navigate, the Quadro handled it much, much better. Minimal lag, and it had no trouble tackling real time shadow generation and ambient occlusion.
Pros: Easy To Install, Easy To Use, Good Graphics Quality