Summary: Very pleased with this purchase. It has allowed me to connect 3 apple monitors together in tandem... A MacBook air, a 24" Cinema Display and a 27"Lightning display. I was about to give up hope that it could be done. It is pricey but worth it for allowing me to marry my 3 favorite monitors into one seamless display.
Summary: I purchased this drive to use as an external boot drive for my iMac. I installed all of my apps and operating system on it intending to increase the speed of my system. It was a success. My system is quite a bit faster than with the internal spinning drive due to the thunderbolt connection and the fast Solid State Drive. Be aware that this drive is two 250 gb drives and not one 500gb.
Summary: I use this as my system startup drive for my mid-2011 27" iMac, and it's awesome. Thanks to this drive this is the first time that I'm not ready to replace a computer after only two years. However next I buy another desktop Mac, I'll just plug this in and not worry about reinstalling anything. It's fast. Unless you've experienced SSD it's hard to convey how fast it is. And aside from the fan noise, it's quiet.
Summary: I am using this for running Intelligent Artifact's GAIuS version 3.0 (big data, artificial intelligence framework) in a Linux (Ubuntu version 12) virtual machine (VMWare Fusion version 4.1.4) on a Macbook Pro running OS X version 10.8.5. GAIuS is very I/O intensive. Using the Macbook Pro's internal hard drive while running very large training data sets would slow down the computer making it difficult to run other applications.
Summary: Applications launch faster, maybe two bounces. Spotlight searches are amazingly fast, no perceptible lag. I cloned the standard 500GB Mac mini internal to the Little Big Disk with Super Duper. It took about four hours for 460GB. Now I boot off the external and do a nightly clone back to keep the internal as a boot-ready backup. I also have a 1.5 TB external data drive and a 2TB external time machine drive. Using the SSD as a boot makes it feel like a much faster machine.