Conclusion: I've found the Off Trail 2 to be very useful. It's not expensive (around $65) and it's very versatile. It may not be the perfect bag - since there is no perfect bag - but it's the best all-round general-purpose bag that I own. I also have a LowePro Trekker backpack which is great for hiking through the woods with a 500/4.5L in it, but when I leave the big lens behind, I often take the Off Trail 2. Highly recommended.